SARMs and Beyond: Emerging Pharmacotherapies Targeting Skeletal Muscle Disorders

The Nanoscale Science Ph.D. Program is an interdisciplinary program of research and teaching that promotes the understanding, development and manipulation of structures and phenomena that have nanoscale dimensions.

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Welcome to the Walter Research Group in the Chemistry Department at UNC Charlotte. We are interested in the synthesis and development of new materials for Solar Energy Conversion. Photoactive materials such as porphyrins are developed in our lab can be used to harvest solar photons and convert that energy into either electricity or into a fuel such as hydrogen. Our work involves testing these materials in organic solar cell, dye-sensitized TiO2 solar cell, or photoelectrochemical cell configurations. Our work spans materials research, organic syntheses, and nanoscience.

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Date: Mon. 18 Mar, 2013 4:00 pm - 5:00 pm

Duration: 1 Hour

Philip Turnbull

GlaxoSmithKline Inc.
Metabolic Pathways and Cardiovascular Therapy Area Unit
Research Triangle Park

Will be presenting

SARMs AND BEYOND: EMERGING PHARMACOTHERAPIES TARGETING SKELETAL MUSCLE DISORDERS

Skeletal muscle is emerging as a key target tissue for drug discovery. Vast opportunities exist for therapeutic interventions targeting muscle wasting, metabolic disorders, contractility, and motor neuron disorders. Selective androgen receptor modulators (SARMs) have arisen as one of the first viable therapies for muscle wasting disorders. Other therapies on the horizon are focused on leveraging negative regulators of muscle mass in the TGF beta signaling pathway.
This seminar will focus the development of SARMs at GSK and how SARMs fit into the context of other pharmacotherapies being developed for skeletal muscle disorders.

Monday, March 18, 2013 @ 4:00pm Rm. 115 Burson
Refreshments served @ 3:45

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